Involvement of gut microbiota in Alzheimer's disease
The gut microbiome has been implicated in numerous neurodegenerative diseases. We were the first to demonstrate that modulation of the gut microbiome of Alzheimer's disease (AD) mice results in improved cognition and pathology (Left - non-treated; Right - treated for 7 days). We are now investigating mechanisms driving these changes in the brain as they will highlight therapeutic avenues for disease modification.
Duration
2023 - Now
Category
Non-pharmacological interventions
Tags
#Gut
#Brain
#Microbiome
The gut microbiome has been implicated in numerous neurodegenerative diseases. We were the first to demonstrate that modulation of the gut microbiome of Alzheimer's disease (AD) mice results in improved cognition and pathology. We are now investigating mechanisms driving these changes in the brain.